Easy bleeding/bruising, stomach upset/pain, diarrhea, and constipation may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless mental physical and long-term effects of salvia use your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. The metabolite of this prodrug inhibits platelet activation and aggregation by binding to P2Y12 receptors on platelets.
What Is the Difference Between Ischemic Stroke and Hemorrhagic Stroke?
Take this medicine exactly as directed by your doctor. Clopidogrel will not work properly if you take less of it than directed. Taking more clopidogrel than directed may increase the chance of serious side effects without increasing the helpful effects. Ask your pharmacist any questions you have about refilling your prescription. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed.
Side effects and risks
For instance, some can interfere with how well a drug works, while others can cause increased side effects. If you have itchy skin, it may go away within a few days or a couple of weeks. If it is more severe or doesn’t go away, talk to your doctor or pharmacist. For more information on the possible biofeedback side effects of clopidogrel, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist. Medicare covers some PGx testing when a consumer and their providers meet certain criteria, including whether a drug being considered has a significant gene-drug interaction.
- Older people may benefit from antithrombotic therapy, but they may have a higher likelihood of bleeding than younger people.
- Sometimes it is not safe to use certain medications at the same time.
- However, drinking too much alcohol while you’re taking Plavix can irritate your stomach.
- Call your doctor right away if you have serious side effects.
What may interact with this medication?
It keeps platelets in your blood from attaching to each other and making blood clots. After six hours, 50% of a typical clopidogrel (Plavix) dose is still in your system. But the effect of clopidogrel on your platelets may last for up to five days, making the risk of bleeding higher for a few days after you stop taking the medication.
Plavix generic
Plavix and Effient have different approved uses, but they’re both used to prevent cardiovascular events in people with ACS. Effient comes as tablets that are taken by mouth twice each day. However, it’s given by having you take more than one tablet of Effient one time at the start of treatment.
You may have heard of a condition related to blood clots called deep vein thrombosis (DVT). DVT means the clot is in a deep vein, usually in your pelvis, thigh, or lower leg, but sometimes in your arm. These clots can break off and travel to your lungs in a life threatening complication called pulmonary embolism. Other drugs may interact with clopidogrel, including prescription and over-the-counter medicines, vitamins, and herbal products. Plavix is used to lower your risk of having a stroke, blood clot, or serious heart problem after you’ve had a heart attack, severe chest pain (angina), or circulation problems. If you are not currently taking aspirin, consult your doctor before starting it for any medical condition.
If you need to take these drugs together, your doctor may adjust your dosage of repaglinide. They’ll also monitor you closely for side effects of the drug. It can also interact with certain supplements as well as certain foods.
This is because Plavix prevents your blood from clotting as it normally would, which can increase your risk of severe bleeding. They’ll discuss the benefits and risks of Plavix with you and may recommend a different treatment for your condition. Do not stop taking this medicine without first talking to your doctor, even if you have signs of bleeding. Stopping clopidogrel may increase your risk of a heart attack or stroke. Clopidogrel is also sometimes used to prevent blood clots in people with atrial fibrillation (a condition in which the heart beats irregularly). Talk to your doctor about the possible risks of using this medication for your condition.
During your Plavix treatment, consider taking notes on any side effects you’re having. This is especially helpful when you first start taking a new drug or using a combination of treatments. Certain side effects of Plavix, such as bleeding and thrombotic thrombocytopenic purpura, can also cause fatigue.
Plavix is used to help prevent blood clots from forming in your body. If you’re taking Plavix, you were probably started on the drug because you had an increased risk of having blood clots. Shortness of breath can be a sign of a dangerous side effect called thrombotic thrombocytopenic purpura (TTP). With TTP, blood clots are formed throughout your body. If you take it every day, clopidogrel stops platelets clumping together to form unwanted blood clots. The Mayo-Baylor RIGHT 10K Study — one of the largest PGx studies ever conducted in the United States — looked at 77 gene variants, most involved with drug metabolism in the liver.
Ask your pharmacist about using these products safely. CLOPIDOGREL (kloh PID oh grel) lowers the risk of heart attack, stroke, or blood clots. how does alcohol use interact with anger It prevents blood cells (platelets) from clumping together to form a clot. It belongs to a group of medications called antiplatelets.
You should avoid taking Plavix with a certain diabetes drug called repaglinide. This because Plavix increases the level of repaglinide in your body, which may increase your risk of certain side effects from repaglinide. While you’re using Plavix, talk with your doctor before you start taking any new medications, including pain relievers. If you need to take something for pain relief while you’re using Plavix, your doctor may recommend that you take acetaminophen (Tylenol) instead of ibuprofen or other NSAIDs.
People who’ve had a stroke in the past have a higher risk of having another one. Call your doctor right away if you have any unexplained shortness of breath while you’re taking Plavix. It’s possible to have blood in your urine during Plavix treatment. However, having blood in your urine may sometimes indicate serious bleeding or kidney problems. You shouldn’t put anything inside your nose to plug or block your nostrils. If your nose continues to bleed for more than 15 minutes, or if the bleeding gets worse before 15 minutes have passed, call your doctor right away.
(An active ingredient is what makes a drug work.) Plavix comes as a tablet you swallow. Studies in rats have shown that clopidogrel appears in breast milk; however, it is not known whether it also appears in human breast milk. Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing clopidogrel to nursing mothers. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Plavix only for the indication prescribed. Plavix may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body. Your doctor may perform a blood test to make sure Plavix is right for you.